Route efficiency assessment and review of the synthesis of ?-nucleosides <i>via N</i>-glycosylation of nucleobases
نویسندگان
چکیده
Instead of focusing on maximizing glycosylation yield, future syntheses nucleosides via N-glycosylation should aim to use shorter routes, fewer protecting groups and less chromatography achieve more efficient sustainable processes, as this E-factor analysis reveals.
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ژورنال
عنوان ژورنال: Green Chemistry
سال: 2021
ISSN: ['1463-9262', '1463-9270']
DOI: https://doi.org/10.1039/d0gc02665d